*Want to be alerted when a specific item on the intranet receives a response or is updated without having to check the intranet all the time?*
Then what you want to do is use "subscriptions." At the bottom of every item, there's a link that says 'subscribe.' Clicking this link will create a subscription to that item. When the item is updated, responded to, or edited, the system will send you an email alerting you to the change. This way, you can keep up to date on items that interest you without constantly checking the site. When you're no longer interested in the topic, just click the "My subscriptions" link on the left which will list the items you're subscribed to, and give you the option of deleting a subscription so that you no longer receive email updates about that item.